Weight Loss Plateau on GLP-1? Here's What's Actually Happening

The scale hasn't moved in weeks. You're doing everything right. What's going on? Before you panic or assume the medication stopped working, let's understand what might actually be happening—and what to do about it.

First: Is It Actually a Plateau?

Weight fluctuates daily—by several pounds—due to factors having nothing to do with fat:

A real plateau: No downward trend for 4-6+ weeks, not just a few days or even a couple weeks. Short stalls are completely normal.

Look at the trend over time, not day-to-day numbers. Weekly averages are more meaningful than any single weigh-in.

Why Real Plateaus Happen

1. Your Body Adapted

As you lose weight, your body requires fewer calories. What created a deficit at 250 lbs might be maintenance at 200 lbs. Your metabolism also adapts to prolonged calorie restriction.

2. Calories Have Crept Up

Appetite suppression can fade slightly over time, or portion sizes gradually increase without noticing. If you're not tracking, you may be eating more than you realize.

3. You're Building Muscle

If you've added exercise (especially strength training), you may be building muscle while losing fat. The scale stays flat, but body composition improves. This is actually good—check how clothes fit or take measurements.

4. Dose Optimization Needed

You may benefit from a dose increase if you haven't reached the maximum and appetite suppression has waned.

5. Normal Weight Loss Patterns

Weight loss isn't linear. People often lose in "stair-step" patterns—periods of loss followed by periods of stability. This is normal physiology, not failure.

Plateau-Breaking Strategies

1. Audit Your Intake

Track everything you eat for one week—accurately, with measurements. You may be surprised. Liquid calories, cooking oils, and "just a bite" moments add up. This isn't about restriction—it's about awareness.

2. Check Your Protein

Are you hitting 60-100g daily? Adequate protein preserves muscle (which keeps metabolism higher) and increases satiety. If protein has slipped, prioritize it.

3. Add or Adjust Exercise

If you're not exercising, start (even walking counts). If you are, change something: increase intensity, add strength training, try a new activity. Bodies adapt to routine—surprise yours.

4. Evaluate Sleep and Stress

Poor sleep increases hunger hormones and cortisol. Chronic stress does the same. These can stall weight loss despite good eating habits. Address lifestyle factors.

5. Discuss Dose with Provider

If you're not at maximum dose and appetite suppression has decreased, a dose increase may help. This is a conversation for your prescribing provider.

6. Consider Medication Timing

Some people find changing injection day or time affects their weekly pattern. There's limited science here, but anecdotally some people find certain timings work better.

What NOT to Do

Reframing the Plateau

Consider: a plateau might be your body stabilizing at a new set point. It's not failure—it's consolidation. The ability to maintain a lower weight for a period IS progress, even if the scale isn't moving.

Some questions to ask yourself:

If yes, you're succeeding—even during a plateau.

When to Talk to Your Provider

Reach out if:

Plateaus are part of the journey. They're frustrating but not permanent. Stay the course, make adjustments where appropriate, and trust the process.

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